> I am low in BH4 which limits my ability to metabolize amino acids down the common pathway and thinks like phenylalanine get metabolized dow the alternative pathways creating PEA and Tyramine. But also I have the mental illness associated changes in TAAR1 and VMAT1 and VMAT2. (I have schizoaffective Bipolar Disorder.)
this is an amazing amount of self knowledge about these topics -
i'm sure some came from introspection, but for the rest - how did you find these things out or are you in the field?
seems like useful knowledge for people to have, aside from problems with over self diagnosis of course
20 years ago my life finally fell apart from my mood disorder that’s heavily genetic in my family on my mother side. So while on disability after leaving my job as a network engineer I decided to go full in and try to find out what part of our genetics was causing this problem.
I had the benefit of living next to a large research hospital which I stayed in three or four times during some of my episodes. But once the Internet really came around my learning grew exponentially.
I have the added benefit of probably having aspergers as well. I also perform countless experiments on myself using different combinations of supplements in diet. Each failure let me to great information about what was going on. Now I’m at a place where I only need klonopin on occasion. This is coming from being on four different medication‘s at once.
seen .. much bettern to hear the song in context in a soundsystem live tape (several on yt) - and possibly with cough cough sacrament - e.g. coxsone, killmanjaro, etc.
<3 the 'digital raggae' electronic pre-dancehall sound
A somewhat Europeanized version of this Dub can often be found behind the query "steppa, steppers or dubtronica" of many platforms such as Spotify. Which, also, is best heard on either good headphones or with your head stuck down a giant soundsystem wall (don't do that, though, seriously)
I get the problem with claiming it to sound 'exotic' or whatever - exactly as you mention - this is 'entitlement' to sound special - but -
Thinking differently -
5 generations is also (assuming childbirth at 25 and not carefully auditing for off-by-ones):
1 generation of 1:1 mix, 4 generations ago (b. 1897)
1 generation of 1:2 mix, 3 generations ago (b. 1922)
1 generation of 1:3 mix, 2 generations ago (b. 1947)
1 generation of 1:4 mix, 1 generations ago (b. 1972)
1 generation of 1:5 mix, now. (b. 1997)
In other words - 50% of your parenting influence descends from 4 generations of mixed marriages, and the entire mixed lineage begins approx ~100 years ago where it certainly would be a huge factor in daily life. It's quite
possible that you may have even met the original couple or their immediate children, and very likely that you met or had extended contact with the 25% generation who in turn almost certainly was extremely impacted by the preceding 2 generations.
Pretty sure there is some cultural trace either overtly or in the form of inherited scars.
The reason many mixed don't know much about their fraction is because their ancestors were put in indian schools and married off to anglo settlers or any number of other far worse 'ethnic cleansing' atrocities. Whatever in-depth discussion remained was likely suppressed or downplayed to facilitate assimilation, leaving only hints and impressions behind in the people. At this point there is no way for them to know anything more about their past even if they wanted to.
pretending it's nothing only makes it worse and grows the divide to the past - which itself is a shift away from native views of history and connectedness to ancestors
> Instead, it’s going to look like traditional ingredients prepared with modern American and occasionally modern Mexican cooking techniques. Without knowledge of the history, that seems like it’s “inauthentic” or “westernized”, but really it’s all we’ve got.
mixing up and confusing south-of-the-border indigenous culture with 'hispanic' and north-of-the-border indigenous culture as 'native american' probably doesn't help this much, dishes aside
Even a restricted NAT should allow for this without explicit port forwarding configuration?
Unless you're doing something like active FTP where it's replying to a different port than the one the request originated from. Which would be a interesting choice for a console designed in like 2018.
It’s a firewall thing not a batting thing. You need a stateful firewall to do that kind of smart port forwarding. Which, to be fair, all consumer routers should have.
Stateless firewalls, however, need to have explicit rules for UDP traffic. So that’s what Nintendo are addressing here.
NAT functionality especially for UDP can be incredibly flaky in a lot of consumer hardware, mangling payloads, randomly dropping associations or having extremely short timeouts, and other plain buggy behaviour.
Used it in a previous ops support gig to build up a mini knowledge base of canned issue responses / topical oneliners - we couldn't install software but could save network drive files; tiddly kept my response system flexible & portable between systems - definitely recommend for this use case
> less expensive than the colocated hardware and the three additional people required to provide support and ensure service levels
i often hear people comparing cloud vs colo but not including more traditional dedicated hardware rental - seems to me this should be pretty similar, maintenance wise to cloud since H/W is handled by the vendor (just need to monitor hardware faults in addition to OS/app layer & notify DC on issues)
The difference is that in cloud you get live migration (generally) that works. So if whatever machine you are on dies, you don’t have an expensive and disruptive rebuild/restore cycle to deal
with.
Since this can take a day+ even once you get new hardware, and architecting most software stacks so you have the redundancy and ability to migrate services around without downtime is hard, and hence expensive if you don’t have the expertise (AND randomly available time), running on dedicated rented hardware really shouldn’t be compared to cloud.
It’s a fundamentally different type of experience for the vast majority of people.
this is an amazing amount of self knowledge about these topics - i'm sure some came from introspection, but for the rest - how did you find these things out or are you in the field?
seems like useful knowledge for people to have, aside from problems with over self diagnosis of course