> Iran has never attacked Israel unless attacked first
I mean, come on dude. You explaining away the actions of Iran's proxies as not the actions of Iran is just ahistorical nonsense at best. They funded them, trained them, and directed their actions.
> Israel is indeed concerned with Iran as a threat, but only because they see the other governments in the region as willing to overlook the Palestinian cause, in exchange for economic links with Israel
The complete lock down of the border between Egypt and the Gaza strip is because Egypt is beholden to Israel? Is that what you're saying here?
> the reason why Israel sees them as a threat is very much because of Iran's interest in the Palestinians
And by "interest" you're referring to backing the most violent terrorist groups in the region, who have the blood of thousands of Israeli citizens on their hands.
3090s are running $1400 now? Wowsers. I thought I was overspending when I bought 6x of them for around $800 a pop.
Might be time to sell, to be honest. It's fun to have that at home, but I can't justify having $10k (with memory, mobo, cpu, etc) sitting in my basement without being fully utilized.
This does not include any particularly large models. But the models it contains (Qwen3.6 27B and Qwen3.6 35B-A3B) are the local models people have been very excited about lately. So they didn't release any larger models, and the models people praise so much are from this most recent release.
If they stop releasing their larger models because they want to monetize, would we expect them to release better small models that can outcompete those?
there's pros and cons to it for them. Clearly, they get good branding (at least in enthusiast circles). Perhaps more important is they get community work on optimization. There have been significant performance uplifts on the Qwen3.6 models from the open-source community since they were launched (at a minimum, multi-token prediction is now working with them. It is almost a 2x token generation speedup)
If I had to bet, it would be on HPV causing a majority of the rise in colorectal cancer. It is a major cause of throat cancer in men[0] and causes almost 100% of cervical cancer in women[1]. We have had a significant increase in anal sex over the past 10+ years[2] and are now seeing an increase in colorectal cancer.
"Britain has found that the proportion of 16- to 24-year-olds engaging in heterosexual anal intercourse has risen from 12.5% to 28.5% over recent decades. Similarly, in the US 30% to 45% of both sexes have experienced it."
Still needs to be studied more as there don't seem to be any large studies yet.
"We found that colorectal tissues from 28 (51%) of 55 patients with colorectal cancer were positive for HPV DNA." [3]
HPV may be associated with a subset of colorectal cancers. Future large-scale multicenter case–control studies with data on risk factors such as lifestyle and sexual behaviour are needed."
Is this the disagreement? How does it disagree with a study showing there might be a link, but that it needs more research - "HPV infection may play a role in colorectal carcinogenesis"?
I'm honestly really confused here. Because the study you linked _agrees_ with the one I linked.
Did you also notice that your link is from 2014 and looked at data from 22 March, 2013(!!) or earlier? Or does the age not matter in this instance, but does matter in the link I provided?
In 2019 (since dates are really important, I guess), the KFF directly stated that the vaccine is targeted to the "...9 strains of HPV associated with most cervical cancer, anal cancer, and throat cancer".
Kinda surprised at the idea that HPV is the cause; at least in the US, there was a fairly large push about 15 years ago to get more people (particularly teenage girls and young women) vaccinated against HPV. Would we not see a corresponding dip in deaths related to HPV-associated cancers by now?
1. The original guidance did not call for boys to get the vaccine. It does now.
2. We're talking about two different age groups. The article talks about those under 50. The group who got the HPV vaccine as part of their normal schedule are now just hitting their early 20s.
There's also still a huge number of people in the US who have HPV. It's really, really common.
"Approximately 42.5 million Americans are infected with HPV and there are at least 13 million new infections annually" [0]
Interestingly, the article calls out HPV directly as a cause of an increase in anal cancers.
"While HPV-related cervical and vaginal cancer rates have decreased since 1999, rates for oropharyngeal and anal HPV-related cancers have increased."
Any idea what the percentage of teenagers who are getting the HPV vaccine is? I'm going to guess it's fairly low at this point given that there tend to be religious objections and also given the growing antivaxx sentiments.
True, but “normal schedule” is hiding a bit of subtlety there: the hpv vaccine was recommended for women up to 26 at the time, so the oldest women who got it then would be pushing 50 now.
Not sure if there's something more recent than this, but it was about 15.5% of adults aged 27-45.
It also notes this:
"Human Papillomavirus (HPV) is the leading sexually transmitted infection in the United States, and 85% of sexually active individuals will be infected at some point in their lifetime"
So, if you're not vaccinated and have had multiple sexual partners, it is rather likely you have or have had HPV.
There are many strains, though, and the vaccine provides coverage against a few of the most harmful, so it's still probably worth getting even if you may have been exposed to a subset of strains.
1. As others have mentioned, males were excluded from vaccination until relatively recently. This seems like such a stupid decision in hindsight. When I (male) got my vaccines, I was told that it wasn't routinely done in boys "because of availability issues", which I took to mean "because it's expensive".
2. Initial vaccines offered protection against 4 strains of HPV, newer vaccines protect against 9. People who got the older vaccines remain susceptible to the other 5 strains.
3. It can take years for an HPV infection to become dangerous or cancerous.
4. This last one is speculative, but I assume that when a woman tests positive for HPV or cervical cancer, their partner is also looked at. With the rates of symptoms and cancers going down in woman, their partners might fall through the gaps: there are no routine tests for males.
The test for males used to be putting acetic acid on the genitalia and looking for spots under a blacklight, right? So what is it now? Blood test for the DNA?
Cost and the statistical property that older people have fewer sexual partners on average. There's also a sort of fatalist assumption that you've already been maximally exposed. If the vaccine was zero cost, you'd give it to everyone.
How do you define cost here? The medical cost of the vaccine and nurse time? Or the risk to health? I'd pay for it out-of-pocket, even as an old. But I wouldn't know where.
I also don't get why this twitter user is linked here, versus all the news articles about this new hardware that have been everywhere over the past number of days.
I also dislike his self-promotion, but his work _is_ well know and, as far as I know, well looked upon. I think he has more expertise and knowledge in this area than most (including what you'd find in the news).
Ahh, thanks, that explains things a little more. I wasn't familiar with the author, and his tweet just read like one of those people on Linkedin who regurgitates knowledge and passes it off as their own insight.
GLM 5.1's smallest model size is 206 GB and really you're probably wanting to run a version that's ~400GB. If you want it to be performant, you're not just running it on a VPS.
And just saying "run it on your own cluster" sort of glosses over the cost of such a cluster.
You used to be able to talk about what you're actually trying to do and Opus would be like "Oh, ok, let's continue". Now, it'll hold fast to whatever its first impression was.
I asked Opus 4.8 to help me find some public PoCs for a vulnerability on a two year old version of some software (that has since been patched and fixed many times). Basically just do a google search for me while I was doing other work. It refused. It stated that it would not help me build an exploit kit.
When I pointed out that a google search for public information was, in fact, not building an exploit kit, it went through a series of justifications on why it would not help me, including just making up things that I said. Really the strangest thing ever.
I mean, come on dude. You explaining away the actions of Iran's proxies as not the actions of Iran is just ahistorical nonsense at best. They funded them, trained them, and directed their actions.
> Israel is indeed concerned with Iran as a threat, but only because they see the other governments in the region as willing to overlook the Palestinian cause, in exchange for economic links with Israel
The complete lock down of the border between Egypt and the Gaza strip is because Egypt is beholden to Israel? Is that what you're saying here?
> the reason why Israel sees them as a threat is very much because of Iran's interest in the Palestinians
And by "interest" you're referring to backing the most violent terrorist groups in the region, who have the blood of thousands of Israeli citizens on their hands.
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